Afumi asks you to deliver some medicine to relieve seasickness.
This quest is available if you have completed the quest Confederate Consternation.
Starting the Quest
Talk to Afumi in the Ruby Sea to begin the quest.
Speak with Aokumo
Go south to the stairs and make your way down until you reach the quest icon on the map. Talk to Aokumo to proceed.
Give the Medicine
Go down the stairs to reach sea level, then go clockwise or counterclockwise around the area with the platforms, to reach the quest icon to the north. Go up the stairs near the quest icon, then talk to the Seasick Doman Recruit to hand over the Landlubber's Best Mate.
Speak with Afumi
Go back to the quest icon on the map and talk to Afumi to complete the quest.