You can find the entrance to Upland Zorana Byroad to the northwest of Ralis Pond.
Cave Location
Upland Zorana Byroad is southwest of Zora's Domain, located at 2861, 0374, 0228, which is northwest of Ralis Pond.
Where is the Shrine?
While in Upland Zorana Byroad, if you unlocked Sensor + and have it scanning for shrines, it will sense a shrine in the area. However, the shrine cannot be reached from this cave. Instead, you need to go south to Ralis Pond, and find the Ralis Channel cave on the east side of the pond. The shrine can be found in Ralis Channel.
Explore the Cave
Up ahead, there are two tunnels, one on the left with a Rock Like in it, and one on the right. The path on the left is blocked by vines at the end, which you might be able to cut through with a boomerang. The path on the right leads to some submerged ruins that you can reveal if you go to the northeast wall and use Ultrahand to lift the wooden gate. Before you go through that gate, go to the east corner of this room to find a tunnel that you revealed, and you will find one of Misko's Treasures, the Climbing Boots.
After that, you can go back to the wooden gate that you opened, place a flat wooden board on the water beyond the wooden gate, stand on it, and use Ascend to reach the area near Upland Zorana Skyview Tower.